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The objective of this announcement is to notify public health andsafety, law enforcement, first responders, clinicians, medical examiners andcoroners, forensic and clinical laboratory personnel, and all other relatedcommunities about new information surrounding the emergent novel syntheticopioid N-pyrrolidino protonitazene (also referred to as “protonitazepyne”). Click Here to view the full PDF

The New Jersey Poison Center (NJPIES) has recently identified a cluster of poisoning casesinvolving tianeptine, a substance with opioid-like effects that is being falsely marketed and soldacross the state in gas stations and online as a dietary supplement. Common names fortianeptine include “gas station heroin,” “ZaZa Red,” or “Neptune’s Elixir” (among others).Tianeptine use can lead to serious health complications and

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National data show need for more research into the factors underlying differences in sex-based vulnerability to drug use Men were significantly more vulnerable than women to overdose deaths involving opioid and stimulant drugs in 2020-2021, according to a new study analyzing death records data from across the United States. The study found that men had a 2–3 times greater rate of overdose

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A Guide for Reducing Opioid Overdose During the Summer Months Background The pervasiveness of fentanyl in the illicit drug supply has contributed to an unprecedented number of fatal and non-fatal overdoses throughout the nation. Unfortunately, Ocean County, New Jersey has felt and witnessed fentanyl’s detrimental effects, as the culture of drug use continues to shift and evolve. Tobring awareness to

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Dear Colleague, The United States Food and Drug Administration (FDA) is communicating to health careprofessionals about serious risks associated with xylazine exposure in humans and considerationsfor management. There are no approved uses of xylazine for humans. FDA is aware that xylazine is increasinglydetected in the illicit drug supply and in drug overdoses; however, individuals who use illicitdrugs may not be

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An animal tranquilizer called xylazine is increasingly being found in the US illicit drug supply and linked to overdose deaths.1 Xylazine—which is not approved for use in people—can be life-threatening and is especially dangerous when combined with opioids like fentanyl.2 Due to its impact on the opioid crisis, fentanyl mixed (adulterated) with xylazine has been declared an emerging threat by the White House’s Office

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Xylazine, a non-opioid veterinary tranquilizer not approved for human use, has been linked to an increasing number of overdose deaths nationwide in the evolving drug addiction and overdose crisis.1 Studies show people exposed to xylazine often knowingly or unknowingly used it in combination with other drugs, particularly illicit fentanyl.1–4 While the full national scope of overdose deaths involving xylazine is unknown, research

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There is an increase in cases of marijuana laced with fentanyl, according to a Washington doctor, with dangerous results. “In my clinical practice and among some of my peers, we’re seeing more kids reporting they thought they were just smoking marijuana, when drug screens show fentanyl — and they would have toxicological, or medical side effects consistent with that,” Dr. Michael

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WASHINGTON (AP) — Vending machines that have long been stocked with snacks are getting repurposed to distribute life-saving supplies to help fight the opioid epidemic. A growing number of cities and local governments are making so-called “harm reduction” items, including the overdose-reversal drug naloxone, available for free via machines. Interest in the approach is expected to grow after U.S. regulators recently

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